ea0022p77 | Bone/Calcium | ECE2010
Polyzos Stergios
, Anastasilakis Athanasios
, Efstathiadou Zoe
, Litsas Ioannis
, Kita Marina
, Panagiotou Athanasios
, Papatheodorou Athanasios
, Arsos Georgios
, Moralidis Efstratios
, Barmpalios Georgios
, Zafeiriadou Efthimia
, Terpos Evangelos
Purpose: High serum homocysteine (HCY) and indirectly deficiency of folate and/or vitamin B12 stimulate bone resorption and adversely affect collagen cross-linking. The aim of this study was the evaluation of serum levels of HCY, folate and vitamin B12 in patients with Pagets disease of bone (PDB) and the effect of zoledronic acid (ZOL) on their serum levels.Methods: This was a prospective open-label cohort study, with a control arm at baseline. Ni...